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It is because tissue repair is multifactorial

Heres what you should know: Safety of Vitamin B12 Injections According to the NHS, Vitamin B12 treatment is considered safe when given correctly under medical supervision, with minimal side effects such as mild discomfort, redness, or swelling at the injection site

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This may be at room temperature [20-25C (68-77F)] or refrigerated [2-8 C (36 -46 F)]